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April 1, 1980CancerOpen Access

Role of metastatectomy without chemotherapy in the management of osteosarcoma in children

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Key result

Metastatectomy without adjuvant chemotherapy resulted in survival for 4 out of 6 children who developed metastases from initially non-metastatic osteosarcoma.

Why the study?

Does metastatectomy without adjuvant chemotherapy result in survival in children with osteosarcoma who develop metastases?

Population

18 consecutive children with initially non-metastatic osteosarcoma, of whom 12 developed metastases and 6…

Design

Case_series

Authors

JBJ. M. V. BurgersHoly Cross HospitalDBDmrt K. BreurThe Netherlands Cancer InstituteODO. A. van DobbenburghUniversity of Groningen

Discussion

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Implication

Should not yet change practice; hypothesis-generating for metastatectomy without chemotherapy in pediatric osteosarcoma metastases.

Study Design

Type

Observational (n=18)

Structured PICO

Does metastatectomy without adjuvant chemotherapy result in survival in children with osteosarcoma who develop metastases?

P
Population
18 consecutive children with initially non-metastatic osteosarcoma, 12 of whom developed metastases and 6 underwent metastatectomy.
E
Exposure
Metastatectomy without adjuvant chemotherapy
O
Outcome
Survivalhard clinical

Metastatectomy without adjuvant chemotherapy can result in survival in a subset of pediatric osteosarcoma patients who develop metastases.

Cite This Study

Burgers et al. (1980) conducted an observational in osteosarcoma (n=18). Metastatectomy without chemotherapy was evaluated on survival. Metastatectomy without adjuvant chemotherapy resulted in survival for 4 out of 6 children who developed metastases from initially non-metastatic osteosarcoma.

synapsesocial.com/papers/6a9e2eb22bf3873a96f9add4https://doi.org/10.1002/1097-0142(19800401)45:7<1664::aid-cncr2820450723>3.0.co;2-n
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Also Consider

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  1. 1Chemotherapy,en bloc resection, and prosthetic bone replacement in the treatment of osteogenic sarcoma1976 · 357 citations
  2. 2Adjuvant multiple drug chemotherapy for osteosarcoma of the extremity1977 · 67 citations
  3. 3Surgical Resection and Adjunctive lmmunotherapy for Selected Patients with Multiple Pulmonary Metastases1973 · 140 citations