Key result
Primary antiphospholipid syndrome was associated with a significantly higher prevalence of valvular lesions compared to healthy volunteers (38% vs 4%, P<0.001).
Why the study?
Is there a higher prevalence of significant heart valve lesions in patients with primary antiphospholipid syndrome compared to healthy volunteers?
Case-Control (n=110)
Yes
Is there a higher prevalence of significant heart valve lesions in patients with primary antiphospholipid syndrome compared to healthy volunteers?
Absolute Event Rate: 38% vs 4%
p-value: p=< 0.001
Valvular heart disease, particularly affecting the mitral and aortic valves, is highly prevalent in patients with primary antiphospholipid syndrome, especially those over 40 years old.
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May support echocardiography in primary antiphospholipid syndrome; leaves open effects on outcomes and management.
Cervera et al. (1991) conducted a case-control in 'Primary' antiphospholipid syndrome (n=110). 'Primary' antiphospholipid syndrome vs. Healthy volunteers was evaluated on Prevalence of valvular lesions (p=< 0.001). Primary antiphospholipid syndrome was associated with a significantly higher prevalence of valvular lesions compared to healthy volunteers (38% vs 4%, P<0.001).
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