Key result
The MB2/MB1 ratio discriminated between acute myocardial infarction patients with earlier versus later reperfusion as early as 50 minutes after reperfusion (P<0.05).
Why the study?
Does the measurement of CK-MB isoforms and the MB2/MB1 ratio allow for early, noninvasive detection of myocardial reperfusion in AMI patients?
Population
16 acute myocardial infarction patients who achieved myocardial reperfusion.
Comparison
Measurement of CK-MB, MB1, MB2, and MB2/MB1… vs Comparison between patients with different…
Design
Cohort
Follow-up
Hours post-reperfusion
Authors
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May support early noninvasive reperfusion assessment in AMI; hypothesis-generating and requires prospective validation before practice change.
Observational (n=16)
Does the measurement of CK-MB isoforms and the MB2/MB1 ratio allow for early, noninvasive detection of myocardial reperfusion in AMI patients?
p-value: p=<0.05
The MB2/MB1 ratio and MB2 isoform show potential for the early, noninvasive detection of myocardial reperfusion in AMI patients.
Christenson et al. (1989) conducted an observational in Acute myocardial infarction (n=16). Earlier myocardial reperfusion vs. Later myocardial reperfusion was evaluated on Discrimination between groups by MB2/MB1 ratio at 50 min after reperfusion (p=<0.05). The MB2/MB1 ratio discriminated between acute myocardial infarction patients with earlier versus later reperfusion as early as 50 minutes after reperfusion (P<0.05).
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