Key result
Higher levels of physical activity, assessed objectively by accelerometer, were independently associated with lower plasma fibrinogen concentrations (β = -0.03, p=0.046) after adjusting for confounders.
Why the study?
Does higher physical activity reduce plasma fibrinogen concentrations in healthy adults without chronic diseases?
Population
1284 healthy adults without chronic diseases from the EVIDENT study cohort, mean age 55.0±13.6 years, 60.90%…
Comparison
Higher physical activity vs Lower physical activity
Design
Cross-sectional
Authors
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Higher activity levels were associated with lower fibrinogen; leaves open whether increasing exercise reduces thrombotic risk in healthy adults.
Cross-Sectional (n=1,284)
Yes
Does higher physical activity reduce plasma fibrinogen concentrations in healthy adults without chronic diseases?
Effect estimate: β = -0.03 (95% CI -0.06 to -0.01)
p-value: p=0.046
Higher levels of physical activity are independently associated with lower plasma fibrinogen concentrations in healthy adults, suggesting a potential mechanism for cardiovascular risk reduction.
Gómez‐Marcos et al. (2014) conducted a cross-sectional in Healthy adults without chronic diseases (n=1,284). Physical activity vs. Lower physical activity (first tertile) was evaluated on Plasma fibrinogen concentrations (β = -0.03, 95% CI -0.06 to -0.01, p=0.046). Higher levels of physical activity, assessed objectively by accelerometer, were independently associated with lower plasma fibrinogen concentrations (β = -0.03, p=0.046) after adjusting for confounders.
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