Key result
Young adults with low birth weight had significantly lower resting muscle sympathetic nerve activity compared to normal birth weight controls (24.7 vs 34.4 bursts/min, P < 0.05).
Why the study?
Does low birth weight alter resting sympathetic nerve activity and baroreflex modulation in healthy young adults?
Case-Control (n=26)
Does low birth weight alter resting sympathetic nerve activity and baroreflex modulation in healthy young adults?
Absolute Event Rate: 24.7% vs 34.4%
p-value: p=< 0.05
Young adults born with low birth weight exhibit significantly lower resting sympathetic nerve activity compared to normal birth weight peers, with preserved baroreflex modulation.
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Hypothesis-generating for birth weight effects on autonomic tone; prospective studies needed before considering cardiovascular risk implications.
Weitz et al. (2003) conducted a case-control in Low birth weight (n=26). Low birth weight (< 2500 g at term) vs. Normal birth weight (3200-3700 g) was evaluated on Resting muscle sympathetic nerve activity (burst frequency) (p=< 0.05). Young adults with low birth weight had significantly lower resting muscle sympathetic nerve activity compared to normal birth weight controls (24.7 vs 34.4 bursts/min, P < 0.05).
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