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A double blind study has shown that topical treatment with a new preparation of I% hydrocortisone in a stabilized carbamide drug delivery system effectively controls atopic eczema without the hazards of potent fluorinated corticosteroids. Clinical evaluation confirms that it is at least as effective as 0·1% betamethasone 17‐valerate. The preparation has the physical properties of both a cream and an ointment and can be used in place of either. It has a high level of patient acceptance and can be used in fissured eczemas without causing any sensations of stinging or smarting.
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Almeyda et al. (1974) studied this question.
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