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April 14, 2025Frontiers in Public HealthOpen Access

Sex differences in prevalence of metabolic syndrome components and contributing factors among psychiatric patients in Saudi Arabia

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Key result

Among psychiatric patients in Saudi Arabia, the most common metabolic syndrome components in females were high waist circumference (87.0%) and high fasting glucose (69.6%), whereas males predominantly exhibited low HDL-C (90.7%) and high waist circumference (85.3%).

Why the study?

The study was conducted to detect sex differences in metabolic syndrome features and risk variables among Saudi participants.

Do metabolic syndrome components and contributing factors differ by sex among psychiatric patients in Saudi Arabia?

Population

144 patients aged 19 to 59 in Saudi Arabia

Comparison

Males vs females

Design

Cross-sectional survey

Authors

AAAli Abdullah AlyousefPSPandurangan Subash‐BabuGAGhedeir M. Alshammari

Discussion

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Member takes

Overview

Sex differences in MS components observed in Saudi psychiatric patients; leaves open generalizability and need for prospective validation before guiding care.

Study Design

Type

Cross-Sectional (n=144)

Multicenter

No

Structured PICO

Do metabolic syndrome components and contributing factors differ by sex among psychiatric patients in Saudi Arabia?

P
Population
144 hospitalized psychiatric patients with metabolic syndrome, aged 19 to 59 years (47.9% female), were evaluated for sex differences in metabolic syndrome components and risk factors.
C
Comparator
Males versus females
O
Outcome
Sex differences in metabolic syndrome components (waist circumference, HDL-C, triglycerides, fasting glucose, and blood pressure) and risk variables.surrogate

Main Result

Absolute Event Rate: 17.39% vs 12%

p-value: p=<0.0001

There are significant sex differences in the prevalence of metabolic syndrome components among psychiatric patients in Saudi Arabia, highlighting the need for sex-specific public health policies.

Limitations

  • Limited sample size to represent the adult population in the area
  • No evaluation of the family's socioeconomic situation and other extraneous variables
  • Only examined inpatients at one mental health hospital, limiting generalizability
  • Cross-sectional design prevents inferring causal relationships

Cite This Study

Alyousef et al. (2025) conducted a cross-sectional in Metabolic syndrome in psychiatric patients (n=144). Female sex vs. Male sex was evaluated on Presence of all five metabolic syndrome components (WC, HDL-C, TG, BP, BS) (p=<0.0001). Among psychiatric patients in Saudi Arabia, the most common metabolic syndrome components in females were high waist circumference (87.0%) and high fasting glucose (69.6%), whereas males predominantly exhibited low HDL-C (90.7%) and high waist circumference (85.3%).

synapsesocial.com/papers/6a9e4a72fb84d39a809bc421https://doi.org/10.3389/fpubh.2025.1579145
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Prevalence of Metabolic Syndrome in Primary Health Care, Riyadh, Saudi Arabia2024
  2. 2The Interplay of Diet, Lifestyle, and Metabolic Risk Among Saudi Adults with Metabolic Syndrome2025
  3. 3Prevalence of metabolic syndrome and its components among patients with various psychiatric diagnoses and treatments: A cross-sectional study2016 · 38 citations
  4. 4Metabolic Syndrome and Cardiometabolic Risk Factors in the Mixed Hypercholesterolemic Populations with Respect to Gender, Age, and Obesity in Asir, Saudi Arabia2022 · 14 citations
  5. 5Age and Gender-Specific Pattern of Cardiovascular Disease Risk Factors in Saudi Arabia: A Subgroup Analysis from the Heart Health Promotion Study2023 · 9 citations