Key result
The presence of a single umbilical artery in a TRAP sequence pregnancy was associated with normal growth and no fetal heart failure in the pump twin.
Why the study?
Twin Reversed Arterial Perfusion sequence often leads to fetal heart failure in the pump twin, but the potential protective role of a single umbilical artery remains unknown.
Does a single umbilical artery protect against fetal heart failure development in the pump twin in TRAP sequence pregnancies?
Case Report (n=1)
No
Does a single umbilical artery protect against fetal heart failure development in the pump twin in TRAP sequence pregnancies?
A single umbilical artery in TRAP sequence pregnancies may act as a protective factor against the development of fetal heart failure in the pump twin by reducing blood flow to the parasitic twin.
May support conservative monitoring in select TRAP cases; leaves open prospective validation before practice change.
Twin Reversed Arterial Perfusion (TRAP) sequence is a rare complication in monochorionic pregnancies, often leading to fetal heart failure (FHF) in the pump twin. We present a 17-year-old primigravida with a monochorionic monoamniotic twin pregnancy presented with an acardiac twin, single umbilical artery (SUA), and multicystic placenta appearance. Throughout the pregnancy, the pump twin exhibited normal growth without signs of FHF. The infant was delivered at 34 weeks via cesarean section, healthy and without cardiac anomalies. The nonexistence of an impacted intrauterine fetal development and FHF of the pump twin in our case may be explained by the presence of one umbilical artery, resulting in less blood flow to the parasitic twin, which can be accepted as a protective factor for the pump twin circulation. Our hypothesis-generating finding that SUA may play a protective role in the development of FHF in pump-twin is promising; however, it remains speculative, and further research is needed to confirm the protective role of SUA for pump-twin outcomes in TRAP pregnancies.
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Ocakoğlu et al. (2025) conducted a case report in Twin Reversed Arterial Perfusion (TRAP) sequence (n=1). Single Umbilical Artery (SUA) was evaluated on Development of fetal heart failure in the pump twin. The presence of a single umbilical artery in a TRAP sequence pregnancy was associated with normal growth and no fetal heart failure in the pump twin.
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