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December 1, 1999Orthopedics

Preoperative Risk Factors Associated With Symptomatic Pulmonary Embolism After Total Knee Arthroplasty

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Key result

Preoperative hemoglobin ≥14 g/L (OR 2.4; 95% CI 1.2-4.6) and bilateral procedures (OR 7.2; 95% CI 1.3-39.6) were significant risk factors for symptomatic pulmonary embolism after total knee arthroplasty.

Why the study?

Are preoperative hemoglobin levels and bilateral procedures associated with an increased risk of symptomatic pulmonary embolism in patients undergoing total knee arthroplasty?

Population

124 consecutive patients undergoing cemented total knee arthroplasty under regional anesthesia for…

Comparison

Preoperative hemoglobin ≥14 g/L and bilateral… vs Preoperative hemoglobin <14 g/L and unilateral…

Design

Case-control

Authors

MMMichael Messieh

Discussion

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Member takes

Overview

Preoperative hemoglobin ≥14 g/L and bilateral procedures are significant risk factors for symptomatic pulmonary embolism after total knee arthroplasty despite warfarin prophylaxis.

Study Design

Type

Case-Control (n=124)

Structured PICO

Are preoperative hemoglobin levels and bilateral procedures associated with an increased risk of symptomatic pulmonary embolism in patients undergoing total knee arthroplasty?

P
Population
124 consecutive patients undergoing cemented total knee arthroplasty under regional anesthesia for osteoarthritis.
E
Exposure
Preoperative hemoglobin ≥14 g/L and bilateral procedures (risk factor assessment)
C
Comparator
Preoperative hemoglobin <14 g/L and unilateral procedures
O
Outcome
Symptomatic pulmonary embolismhard clinical

Main Result

Odds Ratio: 2.4 (95% CI 1.2–4.6)

Preoperative hemoglobin ≥14 g/L and bilateral procedures are significant risk factors for symptomatic pulmonary embolism after total knee arthroplasty despite warfarin prophylaxis.

Cite This Study

Michael Messieh (1999) conducted a case-control in Osteoarthritis (n=124). Preoperative hemoglobin ≥14 g/L vs. Preoperative hemoglobin <14 g/L was evaluated on Symptomatic pulmonary embolism (OR 2.4, 95% CI 1.2-4.6). Preoperative hemoglobin ≥14 g/L (OR 2.4; 95% CI 1.2-4.6) and bilateral procedures (OR 7.2; 95% CI 1.3-39.6) were significant risk factors for symptomatic pulmonary embolism after total knee arthroplasty.

synapsesocial.com/papers/6a9e4c6dbfbdb31ff7055606https://doi.org/10.3928/0147-7447-19991201-08

Topics

Pulmonary embolism
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Symptomatic Pulmonary Embolus After Joint Arthroplasty: Stratification of Risk Factors2013 · 104 citations
  2. 2Mind the clot: Predictors of pulmonary embolism after total knee arthroplasty- An analysis of 150,119 cases2025 · 2 citations
  3. 3The Efficacy of Prophylaxis with Low-Dose Warfarin for Prevention of Pulmonary Embolism following Total Hip Arthroplasty*1997 · 94 citations
  4. 4Predictors and risk factors of pulmonary embolism after total hip arthroplasty: an NSQIP study2024 · 1 citations
  5. 5The Benefit of Aspirin Chemoprophylaxis for Thromboembolism after Total Knee Arthroplasty2006 · 112 citations