Key result
Differential renal vein renin assays identified significantly greater renin activity in the involved kidney in 10 of 17 patients with unilateral renal artery stenosis.
Why the study?
Does differential renal vein renin assay have diagnostic value in determining the functional significance of unilateral renovascular disease in hypertensive patients?
Population
47 hypertensive patients, including 25 without renal artery stenosis, 17 with angiographic evidence of…
Comparison
Renin activity assay in plasma from right and… vs Comparison of renin activity between the…
Design
Cross-sectional
Authors
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Supports differential renal vein renin assays for assessing functional significance in unilateral renovascular hypertension; leaves open need for prospective validation.
Observational (n=47)
Does differential renal vein renin assay have diagnostic value in determining the functional significance of unilateral renovascular disease in hypertensive patients?
Differential renal vein renin assays are valuable for diagnosing the functional significance of apparent unilateral renovascular disease.
B. M. Winer (1967) conducted an observational in Hypertension (n=47). Differential renal vein renin assays vs. Patients without renal artery stenosis was evaluated on Renin activity in the vein of the involved kidney versus the uninvolved kidney. Differential renal vein renin assays identified significantly greater renin activity in the involved kidney in 10 of 17 patients with unilateral renal artery stenosis.
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