Key result
Late evaluation after the Mustard procedure for complete transposition of the great arteries revealed significant cardiovascular abnormalities in 74.5% (35 of 47) of patients.
Observational (n=48)
No
Late follow-up after the Mustard procedure for complete transposition of the great arteries demonstrates a high prevalence of significant cardiovascular abnormalities and mortality, indicating a need for better surgical correction methods.
May warrant enhanced surveillance in Mustard survivors; leaves open optimal long-term strategies pending larger prospective data.
Since 1974, late results of the Mustard procedure for correcting complete transposition of the great arteries have been evaluated by cardiac catheterization, electrocardiography, roentgenography, history, and physical examination of 48 Mayo Clinic patients. Of these, 15 were studied 1 month to 2 years postoperatively because of clinical deterioration. The other 33 had been asymptomatic but were asked to return for hemodynamic reevaluation one-half to 11 years postoperatively. Of the asymptomatic group, 19 underwent exercise electrocardiography prior to catheterization and eight performed supine exercise during catheterization. Cardiac catheterization proved the most effective mode of study. Significant cardiovascular abnormalities (caval obstruction, residual pulmonary stenosis, etc.) were found in 35 of the 47 patients--including 20 of the 33 who were asymptomatic. Eight of the symptomatic group and three of the others have died since this restudy. These poor results warrant renewed effort to devise better methods for correcting complete transposition,
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Hagler et al. (1978) conducted an observational in Complete transposition of the great arteries (n=48). Mustard procedure was evaluated on Significant cardiovascular abnormalities. Late evaluation after the Mustard procedure for complete transposition of the great arteries revealed significant cardiovascular abnormalities in 74.5% (35 of 47) of patients.
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