February 1, 1994Catheterization and Cardiovascular Diagnosis
Is intravascular ultrasound better than quantitative coronary arteriography to assess cardiac allograft arteriopathy?
Key result
Intravascular ultrasound correlated closely with quantitative angiography for lumen measurements in 25 post-transplant patients, but offered advantages in characterizing vessel shape and wall thickness.
Why the study?
Does intravascular ultrasound provide better assessment of cardiac allograft arteriopathy compared to quantitative coronary arteriography in patients following cardiac transplantation?
Population
25 patients following cardiac transplantation (20 < 1 year, 5 > 1 year)
Comparison
Intravascular ultrasound vs Quantitative coronary arteriography
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
May aid allograft vasculopathy assessment; hypothesis-generating and requires prospective validation before practice change.
Study Design
Type
Observational (n=25)
Structured PICO
Does intravascular ultrasound provide better assessment of cardiac allograft arteriopathy compared to quantitative coronary arteriography in patients following cardiac transplantation?
P
Population
25 patients following cardiac transplantation evaluated for allograft arteriopathy using both intravascular ultrasound and quantitative coronary arteriography.
E
Exposure
Intravascular ultrasound
C
Comparator
Quantitative coronary arteriography
O
Outcome
Lumen diameter and area measurements of proximal coronary artery segmentssurrogate
Intravascular ultrasound is superior to quantitative coronary angiography for evaluating cardiac allograft arteriopathy due to its ability to precisely characterize vessel shape and wall thickness.
Cite This Study
Lowry et al. (1994) conducted an observational in Cardiac allograft arteriopathy (n=25). Intravascular ultrasound vs. Quantitative coronary arteriography was evaluated on Lumen diameter and area measurements of proximal coronary artery segments. Intravascular ultrasound correlated closely with quantitative angiography for lumen measurements in 25 post-transplant patients, but offered advantages in characterizing vessel shape and wall thickness.