Key result
Treatment of pacemaker endocarditis with antimicrobials alone is unlikely to be curative, and explantation of the device is recommended in all confirmed cases.
Why the study?
Does explantation of the device improve outcomes compared to antimicrobials alone in patients with pacemaker endocarditis?
Case Report (n=1)
Does explantation of the device improve outcomes compared to antimicrobials alone in patients with pacemaker endocarditis?
Pacemaker endocarditis requires device explantation, as antimicrobial therapy alone is unlikely to be curative.
Answers are grounded in this paper and cite their sources.
Device explantation may be needed in pacemaker endocarditis; single case leaves open comparative efficacy versus antimicrobials alone.
Pacemaker endocarditis remains a rare but potentially life threatening complication of pacemaker implantation. This case illustrates a rare cause of pacemaker endocarditis, Serratia marcescens, the management difficulties that can be faced with such organisms, and the potential indolent nature of pacemaker lead associated endocarditis. A review of the current data for pacemaker endocarditis management suggests that treatment with antimicrobials alone is unlikely to be curative and explantation of the device is recommended in all cases of confirmed pacemaker endocarditis (by echocardiography, in correlation with the patient's clinical condition and inflammatory markers).
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Silva et al. (2009) conducted a case report in Pacemaker endocarditis (n=1). Device explantation vs. Antimicrobials alone was evaluated on Cure of pacemaker endocarditis. Treatment of pacemaker endocarditis with antimicrobials alone is unlikely to be curative, and explantation of the device is recommended in all confirmed cases.
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