Key result
A novel sensorless automatic cardiac output control algorithm for a total artificial heart satisfied basic control requirements of cardiac output response during in vitro mock circulatory system tests.
A novel sensorless automatic cardiac output control algorithm for total artificial hearts successfully met basic hemodynamic control requirements in an in vitro mock circulatory system.
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Supports preclinical TAH control development; leaves open clinical translation pending in vivo validation.
A new automatic cardiac output control algorithm for an implantable electromechanical total artificial heart (TAH) was developed based on the analysis of motor current waveform without using any transducer. The basic control requirements of an artificial heart can be described in terms of three features: preload sensitivity, afterload insensitivity, and balanced ventricular output. In previous studies, transducers were used to acquire information on the hemodynamic states for automatic cardiac output control. However, such a control system has reliability problems with the sensors. We proposed a novel sensorless automatic cardiac output control algorithm (ACOCA) providing adequate cardiac output to the time-varying physiological demand without causing right atrial collapse, which is one of the critical problems in an active filling device. In vitro tests were performed on a mock circulatory system to assess the performance of the developed algorithm and the results show that the new algorithm satisfied the basic control requirements of the cardiac output response.
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Choi et al. (1996) studied Total artificial heart control. Sensorless automatic cardiac output control algorithm (ACOCA) was evaluated on Cardiac output response (preload sensitivity, afterload insensitivity, and balanced ventricular output). A novel sensorless automatic cardiac output control algorithm for a total artificial heart satisfied basic control requirements of cardiac output response during in vitro mock circulatory system tests.
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