Key result
An in vitro one-month running test of the modified total artificial heart demonstrated error-free pumping with a total efficiency of 12.6% at 8 L/min and 10.7% at 6 L/min outflow.
Population
Electromechanical pulsatile total artificial heart (in vitro model)
Design
Preclinical
Follow-up
1 month (in vitro)
Authors
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Supports preclinical optimization of total artificial hearts; leaves open in vivo performance and clinical translation.
Relocating the Hall effect sensor in an electromechanical pulsatile total artificial heart provides stable, error-free pumping in vitro, a critical step toward successful in vivo implantation.
Ohushi et al. (1997) studied this question. Modification of the electrical control system (Hall effect sensor repositioning) was evaluated on Hydrodynamic performance and total efficiency. An in vitro one-month running test of the modified total artificial heart demonstrated error-free pumping with a total efficiency of 12.6% at 8 L/min and 10.7% at 6 L/min outflow.
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