Key result
Transcatheter PDA closure was successfully performed in two pediatric patients with large PDAs, resulting in complete occlusion and sustained reductions in pulmonary artery pressure without complications.
Why the study?
Treatment of patent ductus arteriosus in adults and adolescents is challenging, and studies on percutaneous transcatheter closure in these populations remain limited.
Does transcatheter PDA closure improve symptoms and pulmonary artery pressure in patients with large PDA, including those with Eisenmenger syndrome?
Population
Two patients with large PDA
Design
Case report
Authors
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Transcatheter PDA closure appears feasible in adults; case reports leave open need for larger prospective studies before broader adoption.
Case Report (n=2)
No
Does transcatheter PDA closure improve symptoms and pulmonary artery pressure in patients with large PDA, including those with Eisenmenger syndrome?
Transcatheter closure of large PDA can be successfully and safely performed even in complex cases with subsystemic pulmonary artery pressure, leading to symptom resolution.
Ghiasi et al. (2025) conducted a case report in Patent Ductus Arteriosus (PDA) (n=2). Transcatheter PDA closure was evaluated on Procedural success and pulmonary artery pressure reduction. Transcatheter PDA closure was successfully performed in two pediatric patients with large PDAs, resulting in complete occlusion and sustained reductions in pulmonary artery pressure without complications.
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