Key result
Platelet-rich plasma from a patient with abetalipoproteinemia exhibited impaired aggregation and severely reduced Thromboxane B2 formation due to intrinsic platelet abnormalities and plasma properties.
Population
1 patient with abetalipoproteinemia whose plasma lacks apo-B containing lipoproteins
Comparison
In vitro analysis of platelet-rich plasma and… vs Normal platelets
Design
Case_report
Authors
Loading...
May indicate bleeding risk in abetalipoproteinemia; leaves open platelet-lipid interactions in rare disorders.
Case Report (n=1)
Abetalipoproteinemia leads to abnormal platelet aggregation due to both intrinsic platelet defects and plasma lipid composition.
Surya et al. (1991) conducted a case report in Abetalipoproteinemia (n=1). Abetalipoproteinemia (ABL) plasma vs. Normal plasma/platelets was evaluated on Platelet aggregation and Thromboxane B2 (TxB2) formation. Platelet-rich plasma from a patient with abetalipoproteinemia exhibited impaired aggregation and severely reduced Thromboxane B2 formation due to intrinsic platelet abnormalities and plasma properties.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: