January 1, 1998The Journal of Japan Atherosclerosis SocietyOpen Access

Relationship between lipoprotein(a)and platelet adhesion and aggregation

View Full Paper

Ask AI

Bookmark

Population

222 subjects, including 100 non-smoking healthy volunteers, 81 patients with untreated type IIa…

Design

Cross-sectional

Authors

YFYuichi FusegawaTokai University SGShun-ya GOTOTokai University HTHiromitsu TAMACHIAtrium Health Wake Forest Baptist

Discussion

Member takes

Implication

High Lp(a) linked to platelet hyperaggregability in subgroups; hypothesis-generating for atherothrombotic mechanisms, should not change practice.

Structured PICO

Population

222 subjects, including 100 non-smoking healthy volunteers (females postmenopausal >1 year), 81 patients with untreated type IIa hyperlipidemia, and 41 patients with type IV non-familial hyperlipidemia.

Outcome

Platelet aggregation and formation of small, median, and large platelet aggregates (spontaneous and induced by ADP or epinephrine)surrogate

High lipoprotein(a) levels are associated with increased spontaneous and ADP-induced platelet aggregation in specific subgroups, suggesting a potential mechanism for its atherothrombotic risk.

Limitations

Mechanism of Lp(a) influence on platelet aggregation remains unclear

Cite This Study

Fusegawa et al. (1998) studied this question.

synapsesocial.com/papers/6a6fa01726a7f98052dc4084 https://doi.org/10.5551/jat1973.25.9-10_341

View Full Paper

Ask AI

Bookmark

Implication

High Lp(a) linked to platelet hyperaggregability in subgroups; hypothesis-generating for atherothrombotic mechanisms, should not change practice.

Relationship between lipoprotein(a)and platelet adhesion and aggregation

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Relationship between lipoprotein(a)and platelet adhesion and aggregation

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Also Consider

Also Consider