Key result
A method for reversibly interrupting a closed control circuit in the blood-pressure-regulating system in dogs was developed to allow on-line simulation of carotid-sinus reflex regulatory properties.
Facilitates experimental study of baroreflex properties in dogs; leaves open translation to human blood-pressure regulation.
A method has been worked out by which one of the closed control circuits in the blood‐pressure‐regulating system in the dog can be reversibly interrupted for varying periods of time. Careful studies of the chemistry of the carotid‐sinus blood, using this method, as well as of other conditions described in the literature, make it probable that the chemoreceptor mechanism in the carotid‐sinus region and the C.N.S. remain unaffected in this connection. The method provides the pre‐requisite conditions for on‐line simulation of the regulatory properties of the carotid‐sinus reflex, as regards the baroreceptor function.
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Öberg et al. (1969) studied Blood-pressure regulation. Reversible interruption of closed control circuits in the blood-pressure-regulating system was evaluated on Chemistry of the carotid-sinus blood and baroreceptor function. A method for reversibly interrupting a closed control circuit in the blood-pressure-regulating system in dogs was developed to allow on-line simulation of carotid-sinus reflex regulatory properties.
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