Key result
Increased basal parasympathetic tone significantly correlated with the degree of early ST segment elevation induced by right coronary occlusion during angioplasty.
Why the study?
Does basal parasympathetic tone correlate with heart rate reduction and ECG changes during right coronary angioplasty in patients with angina pectoris?
Observational (n=19)
Does basal parasympathetic tone correlate with heart rate reduction and ECG changes during right coronary angioplasty in patients with angina pectoris?
Increased basal parasympathetic tone, as assessed by spectral analysis of heart rate variability, may augment early ST segment elevation induced by right coronary occlusion during angioplasty.
Answers are grounded in this paper and cite their sources.
Basal parasympathetic tone was associated with greater ST elevation during right coronary occlusion; this observational link leaves open any prognostic or therapeutic implications.
The role of basal parasympathetic tone in reducing the heart rate and causing electrocardiographic (ECG) changes during right coronary angioplasty was evaluated in 19 patients with angina pectoris. To measure parasympathetic tone, time and frequency domain parameters of heart rate variability were assessed using 24 h of ambulatory ECG data recorded before angioplasty. There was an age-dependent reduction in heart rate. However, no parameters of heart rate variability were responsible for the changes in heart rate. In contrast, the degree of ST segment elevation during angioplasty correlated significantly with the high-frequency component of heart rate variability. Therefore, the increased parasympathetic tone, as assessed by spectral analysis, may augment the early ST segment elevation induced by right coronary occlusion.
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Nii et al. (1997) conducted an observational in Angina pectoris (n=19). Basal parasympathetic tone was evaluated on Heart rate reduction and electrocardiographic changes (ST segment elevation) during right coronary angioplasty. Increased basal parasympathetic tone significantly correlated with the degree of early ST segment elevation induced by right coronary occlusion during angioplasty.
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