Key result
Operating in the presence of moderate or severe angiographic vasospasm was associated with worse outcomes, whereas only 1 of 28 patients with absent or mild spasm had an unsatisfactory outcome (P<0.003).
Why the study?
Does the presence of preoperative angiographic vasospasm worsen outcomes in Grade I patients undergoing intracranial operation for ruptured cerebral aneurysm?
Observational (n=35)
Does the presence of preoperative angiographic vasospasm worsen outcomes in Grade I patients undergoing intracranial operation for ruptured cerebral aneurysm?
p-value: p=<0.003
The presence of angiographic vasospasm prior to intracranial operation for ruptured cerebral aneurysm is associated with increased morbidity and mortality, suggesting surgery should be postponed if vasospasm is present.
No takes yet. Share an insight, caveat, or question.
May warrant delaying surgery until vasospasm resolves in Grade I patients; leaves open whether timing modification improves outcomes.
Cooper et al. (1980) conducted an observational in Ruptured cerebral aneurysm with subarachnoid hemorrhage (n=35). Angiographic vasospasm (moderate or severe) vs. Absent or mild angiographic vasospasm was evaluated on Unsatisfactory outcome from operation (morbidity and mortality) (p=<0.003). Operating in the presence of moderate or severe angiographic vasospasm was associated with worse outcomes, whereas only 1 of 28 patients with absent or mild spasm had an unsatisfactory outcome (P<0.003).
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