What question did this study set out to answer?

To evaluate the accuracy of transthoracic real-time three-dimensional echocardiography in detailing the anatomical characteristics of congenital aortic valve stenosis relative to direct surgical observation.

September 20, 2006Cardiology in the Young

Correlations with operative anatomy of real time three-dimensional echocardiographic imaging of congenital aortic valvar stenosis

Q: What is the clinical evidence from this study?

Study design: Cross-Sectional. Population: Congenitally malformed and severely stenotic aortic valve (n=8). Intervention: Trans-thoracic real time three-dimensional echocardiography vs. Operative findings (surgery). Primary outcome: Correlation of anatomic characteristics between 3D echocardiography and surgery.

View Full Paper

Ask AI

Bookmark

Key result

Trans-thoracic real-time three-dimensional echocardiography correctly identified sites of leaflet fusion and closely correlated with surgical assessment of valvar anatomy in all 8 patients.

Why the study?

Does trans-thoracic real-time three-dimensional echocardiography accurately define the anatomic characteristics of congenitally malformed and severely stenotic aortic valves compared to surgical findings in pediatric patients?

Population

8 consecutive pediatric patients requiring aortic valvotomy for congenitally malformed and severely stenotic…

Comparison

Trans-thoracic real-time three-dimensional… vs Operative findings at surgery

Design

Cross-sectional

Authors

SSShankar SadagopanSouthampton Hospital GVGruschen VeldtmanAdult Congenital Heart Disease MSMuthukumaran C. SivaprakasamApollo Hospitals

Discussion

Member takes

Implication

May aid preoperative planning in pediatric aortic stenosis; hypothesis-generating in small series and requires larger prospective validation.

Key Points

To evaluate the accuracy of transthoracic real-time three-dimensional echocardiography in detailing the anatomical characteristics of congenital aortic valve stenosis relative to direct surgical observation.
Conducted a prospective cross-sectional observational study of 8 consecutive pediatric patients (median age 16 weeks, range 1 day to 11 years; median weight 7.22 kg) requiring surgical aortic valvotomy.
Acquired preoperative full-volume loops using a Phillips Sonos 7500 ultrasound system, analyzed with Q lab 4.1 software by a single observer, and compared morphological parameters directly against operative findings.
Transthoracic 3D echocardiography correctly identified the number of leaflets and the exact sites of leaflet fusion in 100% (8/8) of patients, matching surgical assessment.
Fusion between the right and non-coronary leaflets occurred in 50% (4/8) of cases, and dysplastic changes were identified in 3 patients (1 with nodules, 2 with excrescences), corresponding closely to surgical findings.

Study Design

Type

Cross-Sectional (n=8)

Multicenter

Structured PICO

Population

8 pediatric patients (aged 1 day to 11 years) with congenitally malformed and severely stenotic aortic valves requiring aortic valvotomy.

Exposure

Trans-thoracic real-time three-dimensional echocardiography prior to surgery

Comparator

Operative findings at surgery

Outcome

Correlation of anatomic characteristics (valvar orifice diameter, number of leaflets, sites of fusion, dysplasia) between echocardiography and surgerysurrogate

Trans-thoracic real-time three-dimensional echocardiography accurately identifies anatomic characteristics of congenitally malformed aortic valves compared to surgical findings.

Limitations

The definition of nodularity and prognosis of nodules requires a comparative study of patients submitted to balloon dilation versus surgical valvotomy.

Cite This Study

Sadagopan et al. (2006) conducted a cross-sectional in Congenitally malformed and severely stenotic aortic valve (n=8). Trans-thoracic real time three-dimensional echocardiography vs. Operative findings (surgery) was evaluated on Correlation of anatomic characteristics between 3D echocardiography and surgery. Trans-thoracic real-time three-dimensional echocardiography correctly identified sites of leaflet fusion and closely correlated with surgical assessment of valvar anatomy in all 8 patients.

synapsesocial.com/papers/6a9e78e3f097d389bc3800a1 https://doi.org/10.1017/s1047951106000977

View Full Paper

Ask AI

Bookmark

Implication

May aid preoperative planning in pediatric aortic stenosis; hypothesis-generating in small series and requires larger prospective validation.