Key result
Epicardial mapping in 8 dogs showed that spontaneous termination of sustained monomorphic ventricular tachycardia was always preceded by conduction block in the central common pathway.
Why the study?
What are the electrophysiological mechanisms of spontaneous termination of sustained monomorphic ventricular tachycardia in a canine postinfarction model?
Population
8 dogs, 4 to 5 days after one-stage ligation of the left anterior descending coronary artery, with 20…
Design
Preclinical
Authors
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May identify central pathway block as a VT termination mechanism in canine models; leaves open translation to human reentry circuits.
What are the electrophysiological mechanisms of spontaneous termination of sustained monomorphic ventricular tachycardia in a canine postinfarction model?
Spontaneous termination of sustained monomorphic ventricular tachycardia in a postinfarction canine model is consistently preceded by distinct electrophysiological changes leading to conduction block in the central common pathway.
El‐Sherif et al. (1996) studied Sustained monomorphic ventricular tachycardia in the postinfarction heart (n=8). Epicardial activation mapping was evaluated on Electrophysiological mechanisms of spontaneous termination of SMVT. Epicardial mapping in 8 dogs showed that spontaneous termination of sustained monomorphic ventricular tachycardia was always preceded by conduction block in the central common pathway.
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