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January 1, 1991Journal of the Chemical Society Perkin Transactions 1

Counterattack reagent: hexamethyldisilathiane in the conversion of nitro compounds into nitriles

Shwu‐Chen Tsay Paul Gani Jih Ru Hwu

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Abstract

Various primary nitro compounds have been treated with KH in tetrahydrofuran and then with Me3SiSSiMe3 to give potassium thiohydroxamates. These salts were neutralized by an acid and then desulphurized by light to afford nitriles in 78–87% yields. In these reactions, Me3SiSSiMe3 acted as a ‘counterattack reagent’.

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Tsay et al. (1991) studied this question.

synapsesocial.com/papers/6a9e85094bbd51f2272cc5ee https://doi.org/10.1039/p19910001493

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