Key result
The haemoglobin level combined with the CAMI-STEMI score improved the predictive value for MACCE within 30 days after PCI in STEMI patients (AUC 0.639).
Why the study?
The effect of haemoglobin level on the prognosis of STEMI patients remains in dispute, prompting an evaluation of haemoglobin combined with the CAMI-STEMI score after PCI.
Does the combination of haemoglobin level and CAMI-STEMI score improve the prediction of MACCE in STEMI patients after PCI?
Cohort (n=360)
Does the combination of haemoglobin level and CAMI-STEMI score improve the prediction of MACCE in STEMI patients after PCI?
Effect estimate: AUC 0.639
Combining haemoglobin levels with the CAMI-STEMI score modestly improves the prediction of 30-day MACCE in STEMI patients undergoing PCI.
Hb addition to CAMI-STEMI score may enhance 30-day MACCE prediction post-PCI in STEMI; hypothesis-generating and requires prospective validation.
Anaemia and high haemoglobin levels are common in ST elevation myocardial infarction (STEMI) patients, but the effect of the haemoglobin level on the prognosis of STEMI patients remains in dispute. This study aimed to evaluate the prognostic value of the haemoglobin level combined with the CAMI-STEMI score in STEMI patients after percutaneous coronary intervention (PCI). We included 360 STEMI patients who underwent PCI. The patients were divided into 3 groups according to the first haemoglobin value after PCI. Clinical characteristics and the incidence of major adverse cardiovascular and cerebral events (MACCE) during the follow-up period were recorded. The incidence of MACCE in the 3 groups increased with a decrease in the haemoglobin level. Multivariate regression analysis showed that the CAMI-STEMI score was an independent predictor of MACCE incidence at 30 days after PCI and that anaemia was an independent predictor of MACCE incidence at 6 months and 1 year after PCI. A high haemoglobin level was an independent predictor of MACCE incidence at 1 year after PCI. The area under receiver operating characteristic curves (AUCs) of the haemoglobin level, CAMI-STEMI score, and haemoglobin level combined with CAMI-STEMI score predicting the occurrence of MACCE in STEMI patients within 30 days after PCI were 0.604, 0.614, and 0.639, respectively. In conclusion, The CAMI-STEMI score was an independent predictor of MACCE incidence at 30 days after PCI. The haemoglobin level combined with the CAMI-STEMI score improved the predictive value of MACCE in STEMI patients within 30 days after PCI.Trial Registration. This trial was a prospective cohort study and registered with ChiCTR-ROC-17011542 .
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Tang et al. (2019) conducted a cohort in ST-elevation myocardial infarction (STEMI) (n=360). Haemoglobin level combined with CAMI-STEMI score vs. Haemoglobin level alone or CAMI-STEMI score alone was evaluated on Major adverse cardiovascular and cerebral events (MACCE) within 30 days after PCI (AUC 0.639). The haemoglobin level combined with the CAMI-STEMI score improved the predictive value for MACCE within 30 days after PCI in STEMI patients (AUC 0.639).
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