Key result
Temporary shunt insertion during carotid endarterectomy was independently associated with severe postoperative hypotension (OR 2.26; 95% CI 1.09-4.71; p=0.029).
Why the study?
Severe hypotension after carotid revascularization increases perioperative stroke, myocardial infarction, and death, but limited data exist regarding risk factors.
Does temporary shunt insertion increase the risk of severe postoperative hypotension in patients undergoing carotid endarterectomy?
Observational (n=160)
Does temporary shunt insertion increase the risk of severe postoperative hypotension in patients undergoing carotid endarterectomy?
Odds Ratio: 2.26 (95% CI 1.09–4.71)
p-value: p=0.029
Temporary shunt insertion during carotid endarterectomy is independently associated with a more than twofold increased risk of severe postoperative hypotension, supporting a selective shunting strategy.
Severe hypotension after carotid revascularization was associated with higher perioperative stroke and MI risk; hypothesis-generating and should not yet change practice.
Background: Carotid endarterectomy is a recognized method for preventing stroke for both symptomatic and asymptomatic hemodynamically carotid artery stenosis. Hemodynamic depression is more frequently associated with carotid artery stenting, while postoperative hypertension and cerebral hyperperfusion syndrome are known frequent complications after carotid endarterectomy. Severe hypotension after carotid revascularization is associated with a higher risk of perioperative stroke, myocardial infarction, and death, with limited data existing regarding risk factors. This study aims to investigate intraoperative risk factors for severe hypotension after carotid endarterectomy. Methods: A total of 160 patients who underwent carotid endarterectomy were included in this study. Patients with other cardiac conditions that required concomitant cardiac surgery, patients with incomplete medical records, and patients considered high risk for surgery were excluded. Results: The incidence of severe hypotension was 30.6%. Patients with severe hypotension after carotid endarterectomy had a higher incidence of diabetes, moderate mitral valve regurgitation, a history of percutaneous coronary intervention, and higher operative times. Using logistic regression, temporary shunt insertion was independently associated with severe postoperative hypotension (OR = 2.26, 95% CI = 1.09–4.71, p = 0.029). Conclusions: This result favors the selective shunting strategy when performing carotid endarterectomies, especially for those patients with comorbidities predisposing to postoperative complications.
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Robu et al. (2024) conducted an observational in Carotid artery stenosis undergoing endarterectomy (n=160). Temporary shunt insertion vs. No temporary shunt insertion was evaluated on Severe postoperative hypotension (OR 2.26, 95% CI 1.09-4.71, p=0.029). Temporary shunt insertion during carotid endarterectomy was independently associated with severe postoperative hypotension (OR 2.26; 95% CI 1.09-4.71; p=0.029).
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