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The previously reported process of entrapping lipases in hydrophobic organic/inorganic hybride silica gels is extended in that the entrapment by the sol–gel process is performed in the presence of porous glass beads, e.g.(SIRAN®), resulting in the in situ fixation of the sol–gel material on the surface of the support and formation of highly active and mechanically stable heterogeneous biocatalysts.
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Reetz et al. (1996) studied this question.
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