Key result
A 71-year-old man with monophasic synovial sarcoma of the pyriform fossa was successfully treated with transcervical complete excision and adjuvant radiotherapy, remaining disease-free at 1 year.
Why the study?
Head and neck synovial sarcoma is rare, prompting this case report.
Case Report (n=1)
No
Transcervical complete excision followed by adjuvant radiotherapy resulted in 1-year disease-free survival in a rare case of monophasic synovial sarcoma of the pyriform fossa.
Answers are grounded in this paper and cite their sources.
Supports multimodal therapy for rare pyriform fossa synovial sarcoma; leaves open need for larger studies on durability and optimal regimens.
Head and neck synovial sarcoma is rare. We report the case of a 71-year-old man who presented with progressive dysphagia, odynophagia, shortness of breath on exertion and hoarseness of voice. Nasendoscopy revealed a smooth, non-fungating, non-ulcerative mass arising from the left lateral pharyngeal wall. CT showed a well-defined, heterogenous enhancing lesion arising from the left pyriform fossa. Initial biopsy taken was inconclusive and patient underwent a transcervical complete excision of the tumour, where histopathological analysis confirmed the diagnosis of monophasic synovial sarcoma of the left pyriform fossa. This patient also received adjuvant radiotherapy postoperatively and remained disease free 1 year after completion of treatment.
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Ng et al. (2020) conducted a case report in Monophasic synovial sarcoma of the pyriform fossa (n=1). Transcervical complete excision and adjuvant radiotherapy was evaluated on Disease resolution and recurrence. A 71-year-old man with monophasic synovial sarcoma of the pyriform fossa was successfully treated with transcervical complete excision and adjuvant radiotherapy, remaining disease-free at 1 year.
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