Key result
Fractional-dose inactivated poliovirus vaccine was successfully introduced into routine immunization across all Indian states by June 2017 as a dose-sparing strategy.
Why the study?
In response to a global shortage of inactivated poliovirus vaccine, India introduced fractional-dosing into routine immunization, prompting a summary of implementation experiences, challenges, and lessons learnt.
Population
Routine immunization programme across all Indian states
Comparison
Fractional-dose intradermal inactivated poliovirus vaccine vs full-dose intramuscular vaccine
Design
Programme implementation report and case study
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Supports dose-sparing polio vaccination in endemic regions; leaves open questions on sustained immunity and broader applicability.
The staggered introduction of fractional-dose inactivated poliovirus vaccine in India demonstrates a successful, cost-effective strategy to manage global vaccine shortages.
A 2019 study conducted a review in Polio. Fractional-dose inactivated poliovirus vaccine was evaluated. Fractional-dose inactivated poliovirus vaccine was successfully introduced into routine immunization across all Indian states by June 2017 as a dose-sparing strategy.
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