Key result
Noninvasive 24-hour beat-to-beat monitoring documented a circadian rhythm for cardiac output, peripheral vascular resistance, and related cardiovascular variables in healthy subjects.
Observational (n=12)
Continuous noninvasive monitoring confirms circadian rhythms in cardiac output, peripheral vascular resistance, and other hemodynamic variables in healthy subjects.
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Supports noninvasive circadian hemodynamic assessment in health; leaves open disease relevance and chronotherapy trials.
This study aimed to explore the 24-h patterns of stroke volume, cardiac output, and peripheral vascular resistance along with other correlated variables, such as left ventricular ejection time, ejection velocity index, thoracic fluid index, heart rate, and blood pressure. The study was performed on 12 clinically healthy subjects by means of a noninvasive beat-to-beat monitoring using the thoracic electric bioimpedance technique associated with the automated sphygmomanometric recording. Time data series were analyzed by means of chronobiological procedures. The results documented the occurrence of a circadian rhythm for all the variables investigated, giving relevance to the beat-to-beat bioperiodicity of cardiac output and peripheral vascular resistance. Temporal quantification of the investigated variables may be useful for a better insight of the chronophysiology of the cardiovascular apparatus.
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Cugini et al. (1993) conducted an observational in Healthy (n=12). 24-hour noninvasive beat-to-beat monitoring was evaluated on Circadian rhythm of stroke volume, cardiac output, peripheral vascular resistance, and related variables. Noninvasive 24-hour beat-to-beat monitoring documented a circadian rhythm for cardiac output, peripheral vascular resistance, and related cardiovascular variables in healthy subjects.
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