Key result
Beat-to-beat blood pressure variability predicted recurrent stroke (HR 1.47; 95% CI 1.12-1.91; P=0.005) and cardiovascular events independently of mean systolic BP and risk factors.
Why the study?
Does beat-to-beat blood pressure variability predict recurrent stroke and cardiovascular events in patients with recent TIA or nondisabling stroke?
Population
520 consecutive patients within 6 weeks of transient ischemic attack or nondisabling stroke
Comparison
Beat-to-beat blood pressure variability… vs Day-to-day BPV and awake ambulatory BP monitoring
Design
Cohort
Follow-up
2 to 5 years
Authors
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May support rapid beat-to-beat BPV as additional prognostic marker post-TIA/stroke; leaves open incremental value over day-to-day measures.
Cohort (n=520)
Does beat-to-beat blood pressure variability predict recurrent stroke and cardiovascular events in patients with recent TIA or nondisabling stroke?
Hazard Ratio: 1.47 (95% CI 1.12–1.91)
p-value: p=0.005
Beat-to-beat blood pressure variability is a significant independent predictor of recurrent stroke and cardiovascular events in patients with recent TIA or minor stroke, outperforming short-term ambulatory BP monitoring.
Webb et al. (2017) conducted a cohort in transient ischemic attack or nondisabling stroke (n=520). Beat-to-beat blood pressure variability was evaluated on recurrent stroke (HR 1.47, 95% CI 1.12-1.91, p=0.005). Beat-to-beat blood pressure variability predicted recurrent stroke (HR 1.47; 95% CI 1.12-1.91; P=0.005) and cardiovascular events independently of mean systolic BP and risk factors.
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