Key result
In patients with prior TIA or stroke, systolic and diastolic beat-to-beat blood pressure variability progressed significantly over 5.8 years (8.36% and 9.7% respectively, P<0.0001).
Why the study?
Beat-to-beat blood pressure variability is linked to recurrent stroke despite good hypertension control, but progression rates, determinants, and affected patient groups have not been identified.
Design
Prospective cohort study
Follow-up
Median of 5.8 years
Authors
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BPV progression post-TIA/stroke requires characterization; leaves open its role as modifiable target beyond mean BP control.
Cohort (n=188)
p-value: p=<0.0001
Beat-to-beat blood pressure variability progresses significantly over time in high-risk patients post-TIA or stroke, particularly in older females, suggesting a potential new therapeutic target.
Webb et al. (2020) conducted a cohort in Transient ischaemic attack or nondisabling stroke (n=188). Follow-up time was evaluated on Progression of systolic and diastolic beat-to-beat blood pressure variability (SBPV and DBPV) (p=<0.0001). In patients with prior TIA or stroke, systolic and diastolic beat-to-beat blood pressure variability progressed significantly over 5.8 years (8.36% and 9.7% respectively, P<0.0001).
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