Key result
Failed mitral valve repair converted to replacement shows similar five-year survival vs planned replacement.
Why the study?
The consequences of requiring mitral valve replacement following a failed attempt at mitral valve repair during the same operation are unclear.
Does intended mitral valve repair that fails and requires replacement worsen perioperative morbidity, mortality, or five-year survival compared to planned mitral valve replacement in patients undergoing MVR?
Observational (n=1,661)
No
Does intended mitral valve repair that fails and requires replacement worsen perioperative morbidity, mortality, or five-year survival compared to planned mitral valve replacement in patients undergoing MVR?
p-value: p=0.91
Failure of initial mitral valve repair leading to replacement during the same surgery does not adversely affect early or long-term outcomes compared to planned replacement, supporting aggressive attempts at repair.
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Comparable survival after failed repair conversion; hypothesis-generating and should not yet change mitral valve strategy.
Ogami et al. (2026) conducted an observational in Mitral regurgitation requiring mitral valve replacement (n=1,661). Intended mitral valve repair leading to replacement vs. Planned de novo mitral valve replacement was evaluated on Five-year survival (p=0.91). Intended mitral valve repair that failed and required replacement resulted in similar five-year survival (P=0.91) compared to planned de novo replacement, despite longer operative times.
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