Key result
Fatal imipramine intoxication in an 11-month-old boy caused profound alteration of myocardial function and ECG changes during the first 18 hours, leading to irreversible cerebral damage.
Why the study?
What are the ECG and myocardial effects of fatal imipramine intoxication in an infant?
Population
11-month-old boy with fatal imipramine intoxication (n=1)
Design
Case_report
Follow-up
18 hours
Authors
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Imipramine intoxication may cause fatal myocardial dysfunction in infants; this Level 5 case leaves open monitoring strategies.
Case Report (n=1)
What are the ECG and myocardial effects of fatal imipramine intoxication in an infant?
Imipramine intoxication in infants can cause profound myocardial dysfunction and ECG changes, prompting a recommendation for occasional ECG monitoring in children on this therapy.
Fouron et al. (1971) conducted a case report in Imipramine (Tofranil) intoxication (n=1). Imipramine (Tofranil) intoxication was evaluated on ECG changes and myocardial function alteration. Fatal imipramine intoxication in an 11-month-old boy caused profound alteration of myocardial function and ECG changes during the first 18 hours, leading to irreversible cerebral damage.
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