This is the authors' abstract. We don't add key points for this paper.
Models for quantal responses to drugs acting competitively are considered. The models are derived by taking the model for graded responses developed largely by Gaddum and applying the principle that a quantal response occurs when an underlying graded response reaches a critical level of intensity. Dynamic equilibria, between the drugs and receptors in the tissues of the units of biological material, are assumed. Three cases occur:
Answers are grounded in this paper and cite their sources.
No takes yet. Share an insight, caveat, or question.
Hewlett et al. (1964) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: