Key result
Normal baseline HDL-C levels in nonagenarians were significantly associated with higher Barthel Index scores (OR 1.03; 95% CI 1.01-1.05) and fewer prescription drugs, but not with long-term mortality.
Why the study?
Are higher HDL-C levels associated with better functional and cognitive status and lower 3-year mortality in nonagenarians?
Cohort (n=62)
Are higher HDL-C levels associated with better functional and cognitive status and lower 3-year mortality in nonagenarians?
Odds Ratio: 1.03 (95% CI 1.01–1.05)
p-value: p=<0.006
In nonagenarians, higher HDL-C levels are associated with better functional status and lower prescription drug use, but not independently with 3-year mortality.
No takes yet. Share an insight, caveat, or question.
Higher HDL-C links to better function but not mortality in nonagenarians; hypothesis-generating and should not change practice.
Formiga et al. (2011) conducted a cohort in Nonagenarians (n=62). Normal HDL-C levels vs. Low HDL-C levels was evaluated on Higher Barthel Index (BI) scores (OR 1.03, 95% CI 1.01-1.05, p=<0.006). Normal baseline HDL-C levels in nonagenarians were significantly associated with higher Barthel Index scores (OR 1.03; 95% CI 1.01-1.05) and fewer prescription drugs, but not with long-term mortality.
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