Key result
SonoVue was superior to Albunex for improving visualization of endocardial borders, achieving complete left ventricle opacification in 34%-87% of patients compared to 0%-16% with Albunex.
Why the study?
Does SonoVue improve left ventricular endocardial border delineation compared to Albunex in adult patients with suboptimal nonenhanced echocardiograms?
RCT
Blinded
Yes
Does SonoVue improve left ventricular endocardial border delineation compared to Albunex in adult patients with suboptimal nonenhanced echocardiograms?
SonoVue is superior to Albunex for improving left ventricular endocardial border delineation and opacification in patients with suboptimal echocardiograms, with an optimal dose of 2.0 ml.
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Favors SonoVue over Albunex for endocardial border visualization in suboptimal echocardiograms; confirms superiority in an RCT.
Nanda et al. (2002) conducted an RCT in Suboptimal, nonenhanced echocardiogram. SonoVue vs. Albunex and hand-agitated saline was evaluated on Degree of left ventricle opacification (LVO), duration of contrast enhancement, and left ventricular endocardial border delineation (LVEBD). SonoVue was superior to Albunex for improving visualization of endocardial borders, achieving complete left ventricle opacification in 34%-87% of patients compared to 0%-16% with Albunex.
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