Key result
Aortic valve repair yielded good early and mid-term results with 90% to 91% freedom from reoperation at 5 years compared to 94% to 98% for bioprosthetic replacement, making it a viable alternative for young patients.
Why the study?
Does aortic valve repair or the Ross operation improve event-free survival compared to aortic valve replacement with a bioprosthetic valve in young patients with severe aortic regurgitation?
Systematic Review (n=1,338)
Does aortic valve repair or the Ross operation improve event-free survival compared to aortic valve replacement with a bioprosthetic valve in young patients with severe aortic regurgitation?
Aortic valve repair and the Ross operation provide good early and mid-term results and are viable alternatives to bioprosthetic replacement for young patients with severe aortic regurgitation who wish to avoid lifelong anticoagulation.
Authors
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May support repair in select young patients; leaves open need for RCTs to confirm durability vs replacement.
Tourmousoglou et al. (2013) conducted a systematic review in Severe aortic regurgitation (n=1,338). Aortic valve repair vs. Aortic valve replacement with a bioprosthetic valve was evaluated on Freedom from aortic valve reoperation at 5 years. Aortic valve repair yielded good early and mid-term results with 90% to 91% freedom from reoperation at 5 years compared to 94% to 98% for bioprosthetic replacement, making it a viable alternative for young patients.