Key result
A double-layer patch of dacron and pericardium was favored for repairing right ventricular outflow tract defects in dogs due to ease of handling, hemostasis, and tissue incorporation.
Why the study?
Does a specific autogenous or prosthetic material provide superior outcomes for repairing right ventricular outflow tract defects in dogs?
Population
49 dogs with surgically created defects in the right ventricular outflow tract
Comparison
Surgical repair using free atrial appendage… vs Comparison among the different graft materials
Design
Preclinical
Follow-up
6 months
Authors
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Should not inform human RVOT repair; leaves open translational studies of patch materials.
Does a specific autogenous or prosthetic material provide superior outcomes for repairing right ventricular outflow tract defects in dogs?
In a canine model, a double-layer patch of dacron and pericardium was the preferred material for right ventricular outflow tract repair due to favorable surgical and histologic properties.
Egerton et al. (1965) studied Right ventricular outflow tract defects (n=49). Various autogenous and prosthetic grafts (atrial appendage, pericardial, dacron, dacron plus pericardium, Teflon) was evaluated on Graft tolerance, surgical handling, haemostasis, and tissue incorporation. A double-layer patch of dacron and pericardium was favored for repairing right ventricular outflow tract defects in dogs due to ease of handling, hemostasis, and tissue incorporation.
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