Key result
Post-mortem examination of a 3-month-old boy revealed severe arteritic changes typical of periarteritis nodosa, with pertussis vaccination discussed as a potential etiology.
Case Report (n=1)
This case report describes a rare presentation of periarteritis nodosa in a 3-month-old infant with severe coronary artery involvement, potentially originating during fetal life.
Post-mortem examination of a 3-month-old boy revealed severe arteritic changes typical of periarteritis nodosa, with pertussis vaccination discussed as a potential etiology.
Summary Description of a case, that of a 3 months old hoy, in which the clinical picture was that of septic fever, local abscesses (after injections), mild jaundice, hepatic enlargement, and signs of myocardial injury. The diagnosis could not be made during life. Necropsy and microscopical examination disclosed severe arteritic changes in several organs, particularly the coronary arteries and the arteries of the kidneys and suprarenal glands, where changes typical of p.n. were present. The lesions were partly of a chronic, sclerosing type (which might indicate that the disease set in during fetal life). Bacterial cultures post mortem gave a growth of pathogenic microorganism from various organs. Since the disease became manifest clinically, after vaccination against pertussis, this etiology is discussed as well.
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Michael Bohman (1954) conducted a case report in Periarteritis Nodosa (n=1). Vaccination against pertussis was evaluated on Necropsy and microscopical examination findings. Post-mortem examination of a 3-month-old boy revealed severe arteritic changes typical of periarteritis nodosa, with pertussis vaccination discussed as a potential etiology.
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