Key result
An 87-year-old man was diagnosed with rare endobronchial involvement of mantle cell lymphoma after presenting with dyspnea on exertion.
Case Report (n=1)
Endobronchial involvement is a rare presentation of mantle cell lymphoma that can be diagnosed via bronchoscopy and biopsy.
Consider endobronchial lymphoma in unexplained elderly dyspnea; extends recognized extranodal sites of mantle cell lymphoma.
Mantle cell lymphoma (MCL) is a subtype of B-cell non-Hodgkin's lymphoma. Most cases of MCL have extranodal involvement at the time of the initial diagnosis; however, endobronchial involvement is rare. An 87-year-old man was referred to our hospital because of dyspnea on exertion. A chest CT revealed diffuse irregular wall thickening of the trachea and bilateral bronchi. A bronchoscopy revealed a diffuse irregular surface of the tracheal and bilateral bronchial mucosa and polyposis-like lesions. He was diagnosed as having MCL based on an endobronchial biopsy, and the diagnosis was confirmed using immunohistochemical staining.
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Katono et al. (2016) conducted a case report in Mantle cell lymphoma (n=1). An 87-year-old man was diagnosed with rare endobronchial involvement of mantle cell lymphoma after presenting with dyspnea on exertion.
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