Key result
Adherence to pharmacological therapies and lifestyle modifications is a crucial strategy to lower the risk of major cardiovascular events in individuals with peripheral arterial disease.
Adherence to pharmacological therapies and lifestyle modifications are central to managing peripheral arterial disease and lowering the risk of major cardiovascular events.
Emphasizes adherence counseling in PAD now; leaves open need for RCTs to quantify event reduction.
In Brief Peripheral arterial disease (PAD) is a common atherosclerotic disease affecting the quality of life of > 8 million Americans. PAD is characterized by atherosclerotic stenoses of arteries that supply the lower extremities and is associated with a marked increase in the short-term risk of heart attack, stroke, amputation, and death. Adherence to pharmacological therapies and modification of lifestyle factors, including increasing moderate physical activity along with supervised exercise, smoking cessation, and a healthy dietary intake, are central to the successful management of PAD. The improvement of an adverse cardiovascular risk profile is a proven and crucial strategy to lower the risk of major morbid and mortal events for individuals with PAD.
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Steffen et al. (2008) conducted a review in Peripheral Arterial Disease. Pharmacological therapies and lifestyle modification was evaluated. Adherence to pharmacological therapies and lifestyle modifications is a crucial strategy to lower the risk of major cardiovascular events in individuals with peripheral arterial disease.
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