May 30, 2018Diabetes Care
Serial Measurement of Natriuretic Peptides and Cardiovascular Outcomes in Patients With Type 2 Diabetes in the EXAMINE Trial
Why the study?
Does serial measurement of NT-proBNP predict cardiovascular death or heart failure hospitalization in patients with type 2 diabetes and recent acute coronary syndrome?
Population
Patients with type 2 diabetes and a recent acute coronary syndrome event enrolled in the EXAMINE trial
Design
Cohort
Authors
Discussion
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Member takes
Implication
May aid risk stratification in T2D post-ACS; leaves open whether serial monitoring improves outcomes or should guide therapy.
Structured PICO
Does serial measurement of NT-proBNP predict cardiovascular death or heart failure hospitalization in patients with type 2 diabetes and recent acute coronary syndrome?
P
Population
Patients with type 2 diabetes and a recent acute coronary syndrome event enrolled in the EXAMINE trial
I
Intervention
Serial measurement of NT-proBNP at baseline and 6 months
O
Outcome
Composite of cardiovascular (CV) death or hospitalization for heart failurecomposite
Serial monitoring of NT-proBNP in patients with type 2 diabetes and recent acute coronary syndrome is useful for identifying those at highest risk for heart failure events.
Cite This Study
Jarolı́m et al. (2018) studied this question.