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September 1, 1982CirculationOpen Access

Effect of exercise on erythrocyte count and blood activity concentration after technetium-99m in vivo red blood cell labeling.

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Key result

Maximal supine bicycle exercise increased blood radiotracer activity and erythrocyte counts in all 13 subjects, with activity changes correlating with erythrocyte count changes (r = -0.78).

Why the study?

Does maximal supine bicycle exercise alter blood radiotracer concentration and erythrocyte count after technetium-99m red blood cell labeling?

Population

22 subjects after technetium-99m in vivo red blood cell labeling

Comparison

Maximal supine bicycle exercise vs Rest (nonexercised control subjects)

Design

Cohort

Follow-up

20 minutes after termination of exercise

Authors

MKM A KonstamTufts UniversitySTSabah S. TumehPiedmont Atlanta HospitalJWJoshua WynneNorthwestern University

Discussion

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Overview

May require pre/post blood activity sampling for accurate LV volume assessment in radionuclide ventriculography; leaves open validation in larger cohorts.

Study Design

Type

Observational (n=22)

Structured PICO

Does maximal supine bicycle exercise alter blood radiotracer concentration and erythrocyte count after technetium-99m red blood cell labeling?

P
Population
22 subjects (13 exercised, 9 nonexercised controls) evaluated for blood radiotracer concentration after technetium-99m red blood cell labeling.
E
Exposure
Maximal supine bicycle exercise
C
Comparator
Rest (nonexercised control subjects)
O
Outcome
Changes in blood radiotracer concentration (activity) and erythrocyte countsurrogate

Main Result

Effect estimate: r = -0.78

Exercise increases blood radiotracer activity primarily due to an increase in erythrocyte count, highlighting the need to measure blood activity before and after interventions during radionuclide ventriculography to accurately assess left ventricular volume changes.

Cite This Study

Konstam et al. (1982) reported an observational. Maximal supine bicycle exercise vs. Nonexercised control subjects was evaluated on Blood radiotracer concentration and erythrocyte count (r = -0.78). Maximal supine bicycle exercise increased blood radiotracer activity and erythrocyte counts in all 13 subjects, with activity changes correlating with erythrocyte count changes (r = -0.78).

synapsesocial.com/papers/6a9ebdb920336e6580f0ca38https://doi.org/10.1161/01.cir.66.3.638
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Left ventricular volumes by gated equilibrium radionuclide angiography: a new method.1979 · 210 citations
  2. 2Role of the spleen in the peripheral vascular response to severe exercise in untethered dogs1974 · 76 citations
  3. 3Plasma volume changes during rest and exercise in different postures in a hot humid environment1979 · 50 citations