Key result
Intraperitoneal inoculation of human poliomyelitic brain and cord successfully transferred acute epidemic poliomyelitis to monkeys, while other species proved refractile.
Early experimental studies demonstrated that poliomyelitis could be transmitted to monkeys but not to most other common laboratory animals.
No takes yet. Share an insight, caveat, or question.
Monkey model enables poliomyelitis transmission studies; leaves open species specificity and human translation.
John W. Nuzum (1916) studied acute epidemic poliomyelitis. intraperitoneal inoculation of human poliomyelitic brain and cord was evaluated. Intraperitoneal inoculation of human poliomyelitic brain and cord successfully transferred acute epidemic poliomyelitis to monkeys, while other species proved refractile.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: