Key result
Aortic valve cusp repair during reimplantation for tricuspid aortic valves did not affect durability, with 10-year freedom from reoperation of 99% in both groups (P=0.64).
Why the study?
Cusp repair may be needed to produce a competent valve during aortic valve reimplantation, but whether this affects reimplantation durability was unknown.
Does the need for aortic valve cusp repair affect the long-term durability of aortic valve reimplantation in patients with tricuspid aortic valves?
Cohort (n=756)
No
Does the need for aortic valve cusp repair affect the long-term durability of aortic valve reimplantation in patients with tricuspid aortic valves?
Concomitant aortic valve cusp repair during aortic valve reimplantation for tricuspid aortic valves does not negatively impact long-term durability or freedom from reoperation.
Cusp repair may be performed during reimplantation without durability concerns; extends observational data but leaves open need for randomized confirmation.
Objective During aortic valve reimplantation, cusp repair may be needed to produce a competent valve. We investigated whether the need for aortic valve cusp repair affects aortic valve reimplantation durability. Methods Patients with tricuspid aortic valves who underwent aortic valve reimplantation from January 2002 to January 2020 at a single center were retrospectively analyzed. Propensity matching was used to compare outcomes between patients who did and did not require aortic valve cusp repair. Results Cusp repair was performed in 181 of 756 patients (24%). Patients who required cusp repair were more often male, were older, had more aortic valve regurgitation, and less often had connective tissue disease. Patients who underwent cusp repair had longer aortic clamp time (124 ± 43 minutes vs 107 ± 36 minutes, P = .001). In-hospital outcomes were similar between groups and with no operative deaths. A total of 98.3% of patients with cusp repair and 99.3% of patients without cusp repair had mild or less aortic regurgitation at discharge. The median follow-up was 3.9 and 3.2 years for the cusp repair and no cusp repair groups, respectively. At 10 years, estimated prevalence of moderate or more aortic regurgitation was 12% for patients with cusp repair and 7.0% for patients without cusp repair ( P = .30). Mean aortic valve gradients were 6.2 mm Hg and 8.0 mm Hg, respectively ( P = .01). Ten-year freedom from reoperation was 99% versus 99% ( P = .64) in the matched cohort and 97% versus 97%, respectively ( P = .30), in the unmatched cohort. Survival at 10 years was 98% after cusp repair and 93% without cusp repair ( P = .05). Conclusions Aortic valve reimplantation for patients with tricuspid aortic valves has excellent long-term results. Need for aortic valve cusp repair does not affect long-term outcomes and should not deter surgeons from performing valve-sparing surgery.
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Hodges et al. (2023) conducted a cohort in Tricuspid aortic valves undergoing aortic valve reimplantation (n=756). Aortic valve cusp repair vs. No aortic valve cusp repair was evaluated on 10-year freedom from reoperation (matched cohort) (p=0.64). Aortic valve cusp repair during reimplantation for tricuspid aortic valves did not affect durability, with 10-year freedom from reoperation of 99% in both groups (P=0.64).
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