Key result
Bicuspid aortic valves show no difference in reoperation risk versus tricuspid valves following reimplantation.
Why the study?
Does aortic valve reimplantation in bicuspid aortic valves have similar freedom from reoperation compared to tricuspid aortic valves?
Cohort (n=132)
Does aortic valve reimplantation in bicuspid aortic valves have similar freedom from reoperation compared to tricuspid aortic valves?
Aortic valve reimplantation in bicuspid aortic valves provides excellent mid-term durability comparable to tricuspid valves, though postoperative aortic regurgitation is a risk factor for reoperation.
Supports reimplantation in bicuspid valves with comparable mid-term durability; leaves open need for longer-term randomized confirmation.
Aortic valve reimplantation has been shown to be a safe procedure. However, evidences of durability in bicuspid aortic valves (BAVs) are limited in the literature. Between 2002 and 2011, 132 patients (mean age 61 ± 12 years) underwent aortic valve reimplantation. In 24 patients (18%), aortic valve was bicuspid. Mean follow-up was 50 ± 26 months (range 1-102 months) and was 99% complete. In-hospital mortality was 0.8% (1 patient). Survival at 1 and 5 years was 99 and 94%, respectively. Overall freedom from aortic valve reoperation at 1 and 5 years was 96 and 90%, respectively, without significant difference between patients with bicuspid and tricuspid aortic valve. Freedom from aortic valve regurgitation >2+/4+, excluding patients reoperated, was at 1 and 5 years of 100 and 99%, respectively. Patients with valve cusp repair showed a higher rate of aortic valve reoperation; however, only postoperative aortic regurgitation >2+/4+ was significant risk factor for redo procedure at multivariate analysis. Aortic valve reimplantation in BAV without cusp repair provides excellent mid-term results. Further observations and longer follow-up are necessary to determine if BAV sparing, even in the presence of cusps alterations, could allow satisfying durability.
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Malvindi et al. (2012) conducted a cohort in Aortic valve reimplantation (n=132). Bicuspid aortic valve vs. Tricuspid aortic valve was evaluated on Freedom from aortic valve reoperation at 1 and 5 years. Bicuspid aortic valve morphology did not significantly affect the risk of aortic valve reoperation at 1 and 5 years following reimplantation compared to tricuspid valves.
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