Key result
Patients with prior MI or left ventricular aneurysmectomy had significantly decreased ET/PEP, cardiac index, and stroke work index at 2 hours post-operation compared to patients without prior MI.
Why the study?
How does myocardial revascularization surgery or left ventricular aneurysmectomy affect left ventricular function and hemodynamics postoperatively?
Observational (n=30)
How does myocardial revascularization surgery or left ventricular aneurysmectomy affect left ventricular function and hemodynamics postoperatively?
Postoperative depression of left ventricular function following revascularization or aneurysmectomy is largely driven by elevated systemic vascular resistance due to catecholamine hypersecretion, which can be improved with vasodilators.
Prior MI signals higher early postoperative LV impairment risk; leaves open optimal management in this subgroup.
The pre- and postoperative systolic time intervals, hemodynamics and serum catecholamines were studied in 30 patients with successful myocardial revascularization surgery or left ventricular aneurysmectomy and the influence of the surgery on the left ventricular function was evaluated. 1. Significant depression of left ventricular performance was recognized in the group of patients with left ventricular aneurysm as compared to the patients with angina pectoris with or without previous myocardial infarction before the operation. 2. At 2 hours after the operation, signigicant decrease of ET/PEP, cardiac index and stroke work index and marked elevation of systemic vascular resistance were seen in the group of patients with aortocoronary bypass surgery who had previous myocardial infarction and with left ventricular aneurysmectomy as compared to the group of patients without previous myocardial infarction. 3. At 2 hours after the operation, ET/PEP seemed to reflect the left ventricular stroke work and the depression of the left ventricular function was mainly affected by the elevation of systemic vascular resistance due to the hypersecrection of serum catecholamines. 4. Reduction of systemic vascular resistance by vasodilator brought an improvement of EG/PEP, cardiac index and stroke work index.
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FUJIWARA et al. (1979) conducted an observational in Myocardial revascularization surgery or left ventricular aneurysmectomy (n=30). Myocardial revascularization surgery or left ventricular aneurysmectomy vs. Patients without previous myocardial infarction was evaluated on Pre- and postoperative systolic time intervals, hemodynamics and serum catecholamines. Patients with prior MI or left ventricular aneurysmectomy had significantly decreased ET/PEP, cardiac index, and stroke work index at 2 hours post-operation compared to patients without prior MI.
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