What question did this study set out to answer?

To evaluate 40-year outcomes and trends in nationwide liver transplantations, assessing recipient survival, graft longevity, and evolving demographic profiles.

October 1, 2025eGastroenterologyOpen Access

Liver transplantations in Finland over 40 years: evolution and recent trends

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To evaluate 40-year outcomes and trends in nationwide liver transplantations, assessing recipient survival, graft longevity, and evolving demographic profiles.
Nationwide registry study analyzing all liver transplantations performed in Finland from 1982 to 2024 (N = 1,763; mean recipient age 46 years).
Survival analyses were estimated using Kaplan-Meier methodology, and retransplantation rates were calculated via cumulative incidence functions alongside international benchmark criteria.
One-year patient survival improved from 83% in the 1980s to 96% during 2020–2024, with overall 5-, 10-, 20-, and 30-year patient survival rates of 83%, 73%, 53%, and 28%, respectively.
Acute rejection rates decreased from 62% in 1980–1989 to 19% in 2022–2023, while post-transplant kidney-replacement therapy declined to 8% after 2022 following a peak of 26% during 2010–2021.
The 30-year cumulative retransplantation rate reached 13% overall and 28% among patients with primary sclerosing cholangitis.

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Implication

Nationwide registry study demonstrates substantial improvements in liver transplant survival across four decades, highlighting shifting donor demographics and lower rejection rates.

Cite This Study

Åberg et al. (2025) studied this question.

synapsesocial.com/papers/6a9ec8138895c9d7bb192bb0 https://doi.org/10.1136/egastro-2025-100219

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Implication

Nationwide registry study demonstrates substantial improvements in liver transplant survival across four decades, highlighting shifting donor demographics and lower rejection rates.

Liver transplantations in Finland over 40 years: evolution and recent trends

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Discussion

Implication

Cite This Study

Liver transplantations in Finland over 40 years: evolution and recent trends

Key Points

Discussion

Implication

Cite This Study

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