Key result
The DECRO system, a non-invasive connected jacket, was developed to simultaneously monitor cardiac and respiratory functions and activity in unrestrained small animals (180g-3kg) such as rats.
Why the study?
Limited preclinical technology can impair animal welfare and lead to poor-quality data, motivating technologies that meet both ethical and scientific needs in species such as rats.
The DECRO system provides a non-invasive method for simultaneous telemetric monitoring of cardiorespiratory function in unrestrained rats, potentially improving animal welfare and data quality in preclinical research.
In preclinical research, animal welfare is a major foundation for relevant and high-quality data. Due to limited technology features in biomedical research, animal welfare can be impaired leading to poor-quality and irrelevant scientific data. Therefore, there is a growing interest in developing new technologies that are able to deliver satisfactory outcomes for both ethical and scientific needs in widely used species in biomedical research such as rats. A telemetric system was developed to meet these needs in the cardiorespiratory field in small animals within 180 grams-3 kilograms weight range. This system called DECRO is a non-invasive connected jacket designed to simultaneously monitor cardiac and respiratory functions, and activity while animals are unrestrained in their environment. This publication describes recommended procedure to achieve proper recording in rats using this jacket.
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Farès et al. (2020) studied Preclinical research. DECRO system (non-invasive connected jacket) was evaluated. The DECRO system, a non-invasive connected jacket, was developed to simultaneously monitor cardiac and respiratory functions and activity in unrestrained small animals (180g-3kg) such as rats.
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